A Herbal Formula, CGXII, Exerts Antihepatofibrotic Effect in Dimethylnitrosamine-Induced SD Rat Model

Figure 5

mRNA expression of hepatic fibrosis molecules. Real-time PCR was performed to determine the mRNA levels of TGB-β1, PDGF-BB, CTGF, Col 1a1 and TIMP-1, MMP-2 and BAMBI, and Smad7 in hepatic tissues. Expression was normalized as a ratio to β-actin. Data are expressed as the mean ± SD (). and , compared with the normal group. , , and , compared with the DMN group. ^¶Both BAMBI and Smad7 were normalized in the DMN group, and the others were expressed as fold changes, which were normalized in the normal group.

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