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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 5123519, 6 pages
http://dx.doi.org/10.1155/2016/5123519
Research Article

Miconia sp. Increases mRNA Levels of PPAR Gamma and Inhibits Alpha Amylase and Alpha Glucosidase

1Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Pedro de Alba, s/n, Ciudad Universitaria, 66455 San Nicolas de los Garza, NL, Mexico
2Facultad de Odontologia, Universidad Autonoma de Nuevo Leon, Eduardo Aguirre Pequeño y Silao, s/n, Mitras Centro, 64460 Monterrey, NL, Mexico

Received 8 April 2016; Revised 2 June 2016; Accepted 12 June 2016

Academic Editor: Menaka C. Thounaojam

Copyright © 2016 David Mizael Ortíz-Martinez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Chen, Y. Wu, J. Zou, and K. Gao, “α-Glucosidase inhibition and antihyperglycemic activity of flavonoids from Ampelopsis grossedentata and the flavonoid derivatives,” Bioorganic & Medicinal Chemistry, vol. 24, no. 7, pp. 1488––1494, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. J. F. Ascaso, “Diabetes mellitus tipo 2: nuevos tratamientos,” Medicina Clínica, vol. 143, no. 3, pp. 117–123, 2014. View at Publisher · View at Google Scholar
  3. M. E. Ràfols, “Tejido adiposo: heterogeneidad celular y diversidad funcional,” Endocrinología y Nutrición, vol. 61, no. 2, pp. 100–112, 2014. View at Publisher · View at Google Scholar
  4. S. Ghosh and L. Rangan, “Molecular docking and inhibition studies of α-amylase activity by labdane diterpenes from Alpinia nigra seeds,” Medicinal Chemistry Research, vol. 23, no. 11, pp. 4836–4852, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Josabad Alonso-Castro, J. Jose Maldonado-Miranda, A. Zarate-Martinez et al., “Medicinal plants used in the Huasteca Potosina, México,” Journal of Ethnopharmacology, vol. 143, no. 1, pp. 292–298, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. J. M. Serpeloni, G. R. Mazzaron, M. Prates et al., “Experimental and toxicologic pathology cytotoxic and mutagenic evaluation of extracts from plant species of the Miconia genus and their influence on doxorubicin-induced mutagenicity: an in vitro analysis,” Experimental and Toxicologic Pathology, vol. 63, pp. 499–504, 2011. View at Google Scholar
  7. A. J. Richard, T. P. Burris, D. Sanchez-Infantes, Y. Wang, D. M. Ribnicky, and J. M. Stephens, “Artemisia extracts activate PPARγ, promote adipogenesis, and enhance insulin sensitivity in adipose tissue of obese mice,” Nutrition, vol. 30, no. 7-8, pp. S31–S36, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. C.-S. Kong, J.-A. Kim, S.-S. Bak, H.-G. Byun, and S.-K. Kim, “Anti-obesity effect of carboxymethyl chitin by AMPK and aquaporin-7 pathways in 3T3-L1 adipocytes,” Journal of Nutritional Biochemistry, vol. 22, no. 3, pp. 276–281, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Chaiittianan, P. Chayopas, A. Rattanathongkom, P. Tippayawat, and K. Sutthanut, “Anti-obesity potential of corn silks: relationships of phytochemicals and antioxidation, anti-pre-adipocyte proliferation, anti-adipogenesis, and lipolysis induction,” Journal of Functional Foods, vol. 23, pp. 497–510, 2016. View at Publisher · View at Google Scholar
  10. X. C. Tan, K. H. Chua, M. Ravishankar Ram, and U. R. Kuppusamy, “Monoterpenes: novel insights into their biological effects and roles on glucose uptake and lipid metabolism in 3T3-L1 adipocytes,” Food Chemistry, vol. 196, pp. 242–250, 2016. View at Publisher · View at Google Scholar · View at Scopus
  11. H.-L. Kim, J. Park, H. Park et al., “Platycodon grandiflorum A. de candolle ethanolic extract inhibits adipogenic regulators in 3T3-L1 cells and induces mitochondrial biogenesis in primary brown preadipocytes,” Journal of Agricultural and Food Chemistry, vol. 63, no. 35, pp. 7721–7730, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. F. M. Siraj, S. Natarajan, M. A. Huq, Y. J. Kim, and D. C. Yang, “Structural investigation of ginsenoside Rf with PPARγ major transcriptional factor of adipogenesis and its impact on adipocyte,” Journal of Ginseng Research, vol. 39, no. 2, pp. 141–147, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. H. S. Nyambe, J. A. Villa, I. Ifie et al., “Inhibition of human α-amylase by dietary polyphenols,” Journal of Functional Foods, vol. 19, pp. 723–732, 2015. View at Google Scholar
  14. C.-W. Liu, Y.-C. Wang, H.-C. Lu, and W.-D. Chiang, “Optimization of ultrasound-assisted extraction conditions for total phenols with anti-hyperglycemic activity from Psidium guajava leaves,” Process Biochemistry, vol. 49, no. 10, pp. 1601–1605, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Dehghan, Y. Sarrafi, and P. Salehi, “Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran,” Journal of Food and Drug Analysis, vol. 24, no. 1, pp. 179–188, 2016. View at Publisher · View at Google Scholar · View at Scopus
  16. N. C. Ammerman, M. Beier-Sexton, and A. F. Azad, “Growth and maintenance of Vero cell lines,” Current Protocols in Microbiology, 2008. View at Publisher · View at Google Scholar
  17. B. Kling, D. Bücherl, P. Palatzky et al., “Flavonoids, flavonoid metabolites, and phenolic acids inhibit oxidative stress in the neuronal cell line HT-22 monitored by ECIS and MTT assay: a comparative study,” Journal of Natural Products, vol. 77, no. 3, pp. 446–454, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Boncler, M. Różalski, U. Krajewska, A. Podsędek, and C. Watala, “Comparison of PrestoBlue and MTT assays of cellular viability in the assessment of anti-proliferative effects of plant extracts on human endothelial cells,” Journal of Pharmacological and Toxicological Methods, vol. 69, no. 1, pp. 9–16, 2014. View at Publisher · View at Google Scholar
  19. T. Kariharan, G. Nanayakkara, K. Parameshwaran et al., “Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression,” Neurobiology of Aging, vol. 36, no. 3, pp. 1451–1461, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. S. N. Lewis, J. Bassaganya-Riera, and D. R. Bevan, “Virtual screening as a technique for PPAR modulator discovery,” PPAR Research, vol. 2010, Article ID 861238, 10 pages, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. L. Wang, B. Waltenberger, E.-M. Pferschy-Wenzig et al., “Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review,” Biochemical Pharmacology, vol. 92, no. 1, pp. 73–89, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. C. Janani and B. D. Ranjitha, “PPAR gamma gene—a review,” Diabetes and Metabolic Syndrome: Clinical Research and Reviews, vol. 9, no. 1, pp. 46–50, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. G. Oboh, O. B. Ogunsuyi, M. D. Ogunbadejo, and S. A. Adefegha, “Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose,” Journal of Food and Drug Analysis, 2016. View at Publisher · View at Google Scholar