Polysaccharide Extracted from Laminaria japonica Delays Intrinsic Skin Aging in Mice

Figure 1

Dermal thickness is restored in aging mice by LP treatment. Hematoxylin and eosin staining of skin tissue samples revealed a decrease in the thickness of the dermis in aging as compared to young mice, which was mitigated by LP or Vit. E treatment. (a) Young control group; (b) aging model; (c) LP-L; (d) LP-M; (e) LP-H; and (f) Vit. E. Bar: 200 μm. The epidermis is indicated with a white triangle, the dermis with a white rectangle, and the hypodermis with an asterisk. (g) Quantitative analysis of dermal thickness (). Values represent mean ± SD. versus aging model group.

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