Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca²⁺-Activated K⁺ Channels (BK_Ca)

Figure 7

Calycosin and formononetin-induced Ca²⁺ response in HUVEC. (a, b) HUVEC was loaded with Fluo-4 in Tyrode solution containing 2 mM Ca²⁺. Representative graph and relative fluorescence intensity in intracellular Ca²⁺ concentration (), evoked by calycosin (100 μM) and formononetin (100 μM) over the time course (). Data were shown as mean ± SEM. versus control.

(a)

(b)