Tanreqing Injection Attenuates Lipopolysaccharide-Induced Airway Inflammation through MAPK/NF-κB Signaling Pathways in Rats Model

Figure 8

Changes in NF-κB p65 immunohistochemical staining in rat airways. Lung tissues from control rats at (a) 24 h, (b) 48 h, and (c) 96 h, rats exposed to LPS alone at (d) 24 h, (e) 48 h, and (f) 96 h, rats treated with LPS + TRQ 2.8 mL/kg at (g) 24 h, (h) 48 h, and (i) 96 h, and rats treated with LPS + TRQ 5.6 mL/kg at (j) 24 h, (k) 48 h, and (l) 96 h were all analysed by haematoxylin and eosin staining. Scale bars 50 μm. (m) Integrated option density sum (IOD sum) value of positive NF-κB p65 staining in rats. Values are expressed as mean ± SD. means significant difference from the control group; means significant difference from the LPS group and means significant difference between LPS + 2.8 mL/kg TRQ group and LPS + 5.6 mL/kg TRQ group.

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