The Hypoglycemic and Antioxidant Activity of Cress Seed and Cinnamon on Streptozotocin Induced Diabetes in Male Rats
Table 2
Effect of administration of L. sativum and cinnamon methanol extracts for 4 weeks on blood sugar, CML, and IL-6 in diabetic rats.
Statistics
G1 Negative control
G2 Positive control
G3 L. sativum extract
G4 Cinnamon extract
FBS mg/dL
Mean ± SE
92.666 ± 1.145
283.333 ± 2.472
206.333 ± 2.444
147.000 ± 1.211
LSD 0.05 = 6.256
-test
—
−63.63
16.67
53.15
Carboxymethyl lysine (CML)%
Mean ± SE
188.16 ± 2.38
276.00 ± 2.58
243.66 ± 1.72
227.16 ± 1.30
LSD 0.05 = 6.415
-test
—
−24.84
13.53
16.07
Serum interleukin-6 (SIL-6) pg/mL
Mean ± SE
5.600 ± 0.260
24.483 ± 0.892
15.883 ± 0.612
8.733 ± 0.230
LSD 0.05 = 1.864
-test
—
−17.24
6.55
21.77
TIL6 pg/mL
Mean ± SE
48.800 ± 2.010
90.433 ± 1.551
74.216 ± 0.772
63.966 ± 1.275
LSD 0.05 = 4.276
-test
—
−14.14
16.14
12.93
Data are represented as mean ± SE. For -test values, is significant at . For ANOVA analysis, within each row, means with different superscript (a, b, c, or d) are significantly different at , whereas means superscripts with the same letters mean that there is no significant difference at . LSD: least significant difference.