Effect of Aurantii Fructus Immaturus Flavonoid on the Contraction of Isolated Gastric Smooth Muscle Strips in Rats

Figure 4

Effect of AFIF on spontaneous contraction of PCSMS in different Ca²⁺ environment recorded by PL 3508-0028 four-channel recorder. Low concentration (below 3000 μg/mL) of AFIF had no influence on PCSMS contraction. When the concentration of AFIF reached 3000 μg/mL, 6000 μg/mL, and 10000 μg/mL, AFIF decreased the mean contraction amplitude of PCSMS clearly. The diastolic effect of AFIF on PCSMS was most obvious in Ca²⁺-lack environment, and high Ca²⁺ concentration clearly weakened AFIF’s action.