Effect of Aurantii Fructus Immaturus Flavonoid on the Contraction of Isolated Gastric Smooth Muscle Strips in Rats

Figure 5

AFIF’s action on PCSMS contraction amplitude after the pretreatment of L-NAME. , versus control. Neither L-NAME nor NS significantly changed the baseline of PCSMS contraction amplitude (). However, after the incubation of L-NAME for 20 min, the effect of AFIF on PCSMS contraction amplitude was inhibited. When AFIF concentration reached 3000 μg/mL, 6000 μg/mL, and 10000 μg/mL, the mean contraction amplitude of PCSMS incubated with L-NAME was significantly higher than control ().