Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways

<div>The effects of spent coffee grounds SFE on melanin content in H89 (a), Ly294002 (b), and PD98059 (c) treated B16F10 cells, respectively. The results are represented as percentages of the control, and the data are presented as the mean ± SD of three separate experiments. 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Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways 

Figure 4 | Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways 