Personalized Kampo Medicine Facilitated Both Cytotoxic T Lymphocyte Response and Clinical Benefits Induced by Personalized Peptide Vaccination for Advanced Esophageal Cancer

Table 3

Correlation between OS time and humoral factors in either pre- or postvaccination samples.

Factor	Prevaccination		Postvaccination
	Median (pg/mL)	Log-rank test ()	Median (pg/mL)	Log-rank test ()
TGF-	1851	0.0402	1795	0.7702
BAFF	928	0.0613	876	0.006
IL-21	3.654	0.7432	2.869	0.7883
IP-10	146	0.0566	203	0.2412
Hp	1407	0.0287	1128	0.1226
IL-1	1.032	0.4875	1.061	0.6922
IL-10	1.517	0.9446	1.681	0.7752
IL-6	5.656	0.0181	7.652	0.0142
GM-CSF	0.481	0.7079	0.506	0.6450
IL-5	0.761	0.9932	0.761	0.1527
IFN-	1.609	0.716	1.638	0.6320
TNF-	1.930	0.1800	1.998	0.2123
IL-2	0.503	0.9772	0.536	0.8641
IL-4	1.241	0.6980	1.355	0.5126
IL-8	4.644	0.0355	3.548	0.0178

TGF: transforming growth factor beta, BAFF: B-cell activating factor belonging to the tumor necrosis factor family, IL: interleukin, IP: interferon-inducible protein, Hp: haptoglobin, GM-CSF: granulocyte macrophage colony-stimulating factor, and TNF: tumor necrosis factor.