Research Article

Ethyl Acetate Fraction of Amomum xanthioides Exerts Antihepatofibrotic Actions via the Regulation of Fibrogenic Cytokines in a Dimethylnitrosamine-Induced Rat Model

Table 2

Organ weights and serum biochemistries.

NaiveDMNEFAX 25EFAX 50Sily 50

Total body mass (g)334.50 ± 18.61243.30 ± 29.76###286.00 ± 17.75267.33 ± 31.29268.83 ± 28.09
Absolute liver mass (g)10.31 ± 0.888.82 ± 1.709.76 ± 1.159.60 ± 1.079.88 ± 1.68
Relative liver mass (g/100 g)3.07 ± 0.163.61 ± 0.37#3.41 ± 0.283.60 ± 0.223.67 ± 0.46
Absolute spleen mass (g)0.76 ± 0.061.44 ± 0.27###1.41 ± 0.211.25 ± 0.261.86 ± 0.35
Relative spleen mass (g/100 g)0.23 ± 0.020.59 ± 0.10###0.50 ± 0.080.48 ± 0.160.70 ± 0.15

AST (IU/L)173.33 ± 24.22848.00 ± 421.51326.66 ± 76.33432.00 ± 106.161100.00 ± 715.29
ALT (IU/L)33.33 ± 10.32514.00 ± 162.26###226.66 ± 70.89388.00 ± 140.60513.33 ± 258.97
Total bilirubin (g/dL)0.10 ± 0.001.20 ± 0.54###0.36 ± 0.050.40 ± 0.081.20 ± 0.15
Platelet (k/L)933.83 ± 41.16222.83 ± 29.68###550.66 ± 164.00368.66 ± 215.3271.50 ± 106.87

, compared to Naïve group; , compared to the DMN group ().