Cognitive-Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice

Figure 2

(a) Effect of A. melanocarpa berries extract on the escape latency of scopolamine-treated mice in the Morris water maze test. A. melanocarpa berries extract (100 and 200 mg/kg body weight, PO), cyanidin-3-O-galactoside (50 mg/kg body weight, PO), and donepezil (1 mg/kg body weight, PO) were administered 90 min before induction of memory impairment by scopolamine. The escape latency of each group during the training-session trials is presented. (b) Mean distance and (c) swimming speed to find the platform over 4 days. (d) Effect of A. melanocarpa extract in the probe trial. The time spent in the target quadrant during the probe trial is presented. Data are mean escape latencies ± SD (). ( and versus the control group; , , and versus scopolamine-treated mice.) Sco: scopolamine.

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