Research Article

Herb-Drug Interaction: Effects of Relinqing® Granule on the Pharmacokinetics of Ciprofloxacin, Sulfamethoxazole, and Trimethoprim in Rats

Table 1

Main pharmacokinetic parameters of ciprofloxacin alone (control) and after repeated administration of RLQ ().

ParametersControl group 1RLQ group 1

(mg/Lh)11.75 ± 4.355.88 ± 1.28
(h)3.16 ± 1.295.89 ± 2.24
(h)1.58 ± 0.491.67 ± 0.52
(L/h/kg)10.14 ± 3.1419.12 ± 4.18
(L/kg)49.81 ± 31.06155.24 ± 47.10
(mg/L)3.52 ± 1.321.03 ± 0.30

when compared with related parameters of control group 1. when compared with related parameters of control group 1.