Xianfanghuomingyin, a Chinese Compound Medicine, Modulates the Proliferation and Differentiation of T Lymphocyte in a Collagen-Induced Arthritis Mouse Model

Figure 5

XFHM enhanced CD4⁺IL-4⁺ Th2 cells differentiation and the production of IL-4 and GATA-3. (a) and (b) The percentage of CD4⁺IL-4⁺ Th2 cells in spleen isolated from mice treated for 4 weeks. (c) The level of IL-4 in sera of mice detected by ELISA. The results are presented in the bar chart. (d) GATA-3 was detected in whole spleen tissue lysates by western blot analysis. GAPDH was used as an internal control. Data are presented as means ± SD. , compared to the normal group; , compared to the model group.

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