Xianfanghuomingyin, a Chinese Compound Medicine, Modulates the Proliferation and Differentiation of T Lymphocyte in a Collagen-Induced Arthritis Mouse Model

Figure 7

XFHM increased CD4⁺CD25⁺FOXP3⁺ Tregs differentiation. (a) The percentages of CD4⁺ T cells in peripheral bloods (PB) and spleens of mice. Lymphocytes were gated in total cells ((a1) PB, (a2) spleen); (a1) and (a2) are the percentages of CD4⁺ T cells in PB and spleens. (b1) and (b2) are the percentages of CD4⁺CD25⁺FOXP3⁺ Treg cells in PB and spleens of mice after treatment for 4 weeks. (c) The results are presented in the bar chart. Data are presented as means ± SD. , compared to the normal group; , compared to the model group.

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