Effects of Yishen Pinggan Recipe on Renal Protection and NF-κB Signaling Pathway in Spontaneously Hypertensive Rats

Figure 4

Impacts of YPR on NF-κB activity in renal tissues. (a) Compared with the WKY group, in the SHR group, IκB-α expression was significantly reduced and nuclear NF-κB/P65 expression level was significantly increased, while the IκB-α expression was not inhibited and nuclear NF-κB/P65 expression was not increased after the Bena and YPR were administered, indicating that YPR could inhibit the nuclear translocation of NF-κB/P65 and degradation of IκB-α. (b) IκB-α expression: compared with the WKY group ; compared with the SHR group . (c) NF-κB/P65 expression levels: compared with the WKY group ; compared with the SHR group .

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