Effect of Alkaloids Isolated from Phyllodium pulchellum on Monoamine Levels and Monoamine Oxidase Activity in Rat Brain

Figure 3

Effects displayed by P. pulchellum on MAO-A and MAO-B activity. P. pulchellum alkaloid was tested in ten different concentrations ranging from 0.1 to 500 μg/mL. The degree of inhibition IC₅₀ was assessed by a sigmoidal dose-response curve. Each point represents the mean ± SMD of the sigmoidal regression for three independent determinations.