Endothelium-Dependent Vasorelaxant Effects of Dealcoholized Wine Powder of Wild Grape (Vitis coignetiae) in the Rat Thoracic Aorta

Figure 1

The vasorelaxant effect of WGWP in rat aortic rings preconstricted with norepinephrine. Isolated rat aortic rings without (a) or with (b, c) endothelium were preconstricted by addition of 300 nM norepinephrine (NE) and vasorelaxation was measured after treatment with WGWP ((a, b) 1 mg/mL; (c) 0.01–1.0 mg/mL). with different letters are significantly different () by one-way analysis of variance.

(a)

(b)

(c)