Attenuation of Thrombosis by Crude Rice (Oryza sativa) Bran Policosanol Extract: Ex Vivo Platelet Aggregation and Serum Levels of Arachidonic Acid Metabolites
Table 1
Full blood count analysis using hematology analyzer (baseline: day 0 of treatment; final reading: day 30 of treatment).
Groups
RBC (1012/L)
MCV
RDW
HCT
PLT (109/L)
MPV (fl)
HGB (g/L)
MCH (pg)
MCHC (g/L)
(fl)
(%)
(%)
NP (before treatment)
8.005 ± 0.04
53.95 ± 0.35
10.7 ± 2.12
40.85 ± 3.75
712 ± 97.58
6.7 ± 0.14
148.5 ± 9.19
19.75 ± 0.64
367 ± 14.14
HFD (before treatment)
7.49 ± 0.68
48.58 ± 1.36
14.35 ± 1.32
36.21 ± 3.23
844.25 ± 157.46
6.93 ± 0.12
133.78 ± 10.45
17.91 ± 0.78
366.3 ± 6.70
NP (after treatment)
7.21 ± 1.01
52.97 ± 1.89
13.83 ± 2.46
38.1 ± 4.42
730 ± 97.58
7.27 ± 0.45
138.67 ± 20.50
19.27 ± 0.72
363.67 ± 13.65
HFD-NC (after treatment)
7.8 ± 0.71
49.47 ± 1.29
13.53 ± 0.67
38.53 ± 2.51
1155.33 ± 160.55
6.77 ± 0.06
143.33 ± 8.08
18.37 ± 0.67
372 ± 3.61
500 mg/kg
7.66 ± 1.04
47.27 ± 1.88
15.53 ± 0.67
36.3 ± 6.16
756 ± 86.27
7.53 ± 0.91
131.67 ± 23.44
17.13 ± 1.03
362.33 ± 8.74
250 mg/kg
8.29 ± 0.25
47.37 ± 1.25
14.87 ± 0.84
39.3 ± 1.31
961 ± 147.89
7.13 ± 0.40
143.33 ± 4.62
17.27 ± 0.55
365 ± 2
100 mg/kg
7.86 ± 0.31
48.23 ± 1.32
15.23 ± 1.67
37.9 ± 1.4
772 ± 288.5
7.13 ± 0.61
138 ± 6.08
17.57 ± 0.40
364 ± 3.46
Aspirin-PC
8.31 ± 0.23
46.53 ± 0.81
15.3 ± 1.42
38.67 ± 0.64
902 ± 106.07
7 ± 0.7
140.33 ± 3.51
16.87 ± 0.23
363 ± 3.61
NC: negative control; PC: positive control; NP: rats which consume normal pellet; HFD: rats which consume high fat diet throughout 3 months study period, . The presented value was mean ± standard deviation. Means that shared the same letter were not significantly different at .
