A 56-Day Oral Toxicity Study of the Aqueous Extract of Rapanea melanophloeos (L.) Mez in Rats

Figure 6

Clinical chemistry parameters of rats dosed with the aqueous extract of Rapanea melanophloeos stem bark for 56 days. Samples were obtained and analyzed fortnightly; (a) alanine aminotransferase activity, (b) creatine kinase activity, (c) blood urea nitrogen, and (d) creatinine. Overall values are the summary of readings at all time points. indicates significant difference from the control means (, two-way ANOVA followed by Fisher’s PLSD post hoc test); # indicates significant difference from pretreatment readings (). Values are different from reference ranges [25].

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