Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2016 (2016), Article ID 7480971, 10 pages
http://dx.doi.org/10.1155/2016/7480971
Research Article

The Fruit Hull of Gleditsia sinensis Enhances the Anti-Tumor Effect of cis-Diammine Dichloridoplatinum II (Cisplatin)

1School of Korean Medicine, Pusan National University, Yangsan 50621, Republic of Korea
2Department of Internal Medicine, Korean Medicine Hospital of Pusan National University, Yangsan 50621, Republic of Korea
3Lung Cancer Clinic, Pulmonary Medicine Center, Pusan National University Yangsan Hospital, Yangsan 50621, Republic of Korea
4Department of Internal Medicine, School of Medicine, Pusan National University, Yangsan 50621, Republic of Korea
5Department of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea

Received 26 May 2016; Accepted 18 August 2016

Academic Editor: Siyaram Pandey

Copyright © 2016 Kyun Ha Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, and M. J. Thun, “Cancer statistics, 2009,” CA: Cancer Journal for Clinicians, vol. 59, no. 4, pp. 225–249, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Ferlay, I. Soerjomataram, R. Dikshit et al., “Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012,” International Journal of Cancer, vol. 136, no. 5, pp. E359–E386, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. K.-W. Jung, Y.-J. Won, H.-J. Kong et al., “Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2012,” Cancer Research and Treatment, vol. 47, no. 2, pp. 127–141, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Ball, A. Mitchell, D. Giroux, and R. Rami-Porta, “Effect of tumor size on prognosis in patients treated with radical radiotherapy or chemoradiotherapy for non-small cell lung cancer. An analysis of the staging project database of the International Association for the Study of Lung Cancer,” Journal of Thoracic Oncology, vol. 8, no. 3, pp. 315–321, 2013. View at Google Scholar
  6. A. Spira and D. S. Ettinger, “Multidisciplinary management of lung cancer,” The New England Journal of Medicine, vol. 350, no. 4, pp. 379–392, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. S. G. Li, H. Y. Chen, C. S. Ou-Yang et al., “The efficacy of chinese herbal medicine as an adjunctive therapy for advanced non-small cell lung cancer: a systematic review and meta-analysis,” PLoS ONE, vol. 8, no. 2, Article ID e57604, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Kuang and K. Zhang, Pharmacopoeia of the People's Republic of China, vol. 1 of Chinese Pharmacopoeial Commission, People's Medical Publishing House, Beijing, China, 2005.
  9. J.-Y. Choi, M. J. Kwun, K. H. Kim et al., “Protective effect of the fruit hull of Gleditsia sinensis on LPS-induced acute lung injury is associated with Nrf2 activation,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 974713, 11 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. K. H. A. Kim, M. J. U. Kwun, C. W. O. Han, K.-T. Ha, J.-Y. Choi, and M. Joo, “Suppression of lung inflammation in an LPS-induced acute lung injury model by the fruit hull of Gleditsia sinensis,” BMC Complementary and Alternative Medicine, vol. 14, article 402, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. L. M. C. Chow, J. C. O. Tang, I. T. N. Teo et al., “Antiproliferative activity of the extract of Gleditsia sinensis fruit on human solid tumour cell lines,” Chemotherapy, vol. 48, no. 6, pp. 303–308, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. F. Cheung, C. H. Chui, A. S. C. Chan et al., “Inhibition of proteasome activity in Gleditsia sinensis fruit extract-mediated apoptosis on human carcinoma cells,” International Journal of Molecular Medicine, vol. 16, no. 5, pp. 925–929, 2005. View at Google Scholar · View at Scopus
  13. I. T. N. Teo, J. C. O. Tang, C. H. Chui et al., “Superoxide anion is involved in the early apoptosis mediated by Gleditsia sinensis fruit extract,” International Journal of Molecular Medicine, vol. 13, no. 6, pp. 909–913, 2004. View at Google Scholar · View at Scopus
  14. S.-J. Lee, Y.-H. Cho, H. Kim et al., “Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo,” Oncology Reports, vol. 22, no. 6, pp. 1505–1512, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. S.-J. Lee, K. Park, S.-D. Ha, W.-J. Kim, and S.-K. Moon, “Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression,” Phytotherapy Research, vol. 24, no. 12, pp. 1870–1876, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. S.-J. Lee, D. H. Ryu, C. J. Lee, S.-C. Cho, W.-J. Kim, and S.-K. Moon, “Suppressive effects of an ethanol extract of Gleditsia sinensis thorns on human SNU-5 gastric cancer cells,” Oncology Reports, vol. 29, no. 4, pp. 1609–1616, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. W. K. Tang, C. H. Chui, S. Fatima et al., “Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma,” International Journal of Molecular Medicine, vol. 19, no. 6, pp. 953–960, 2007. View at Google Scholar · View at Scopus
  18. K. C. Pak, K. Y. Lam, S. Law, and J. C. O. Tang, “The inhibitory effect of Gleditsia sinensis on cyclooxygenase-2 expression in human esophageal squamous cell carcinoma,” International Journal of Molecular Medicine, vol. 23, no. 1, pp. 121–129, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. J.-M. Yi, J. Kim, J.-S. Park et al., “In vivo anti-tumor effects of the ethanol extract of Gleditsia sinensis thorns and its active constituent, cytochalasin H,” Biological and Pharmaceutical Bulletin, vol. 38, no. 6, pp. 909–912, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. L. M. C. Chow, C. H. Chui, J. C. O. Tang et al., “Gleditsia sinensis fruit extract is a potential chemotherapeutic agent in chronic and acute myelogenous leukemia,” Oncology Reports, vol. 10, no. 5, pp. 1601–1607, 2003. View at Google Scholar · View at Scopus
  21. L. Zhong, G. Qu, P. Li, J. Han, and D. Guo, “Induction of apoptosis and G2/M cell cycle arrest by gleditsioside E from Gleditsia sinensis in HL-60 cells,” Planta Medica, vol. 69, no. 6, pp. 561–563, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Rozencweig, D. D. Von Hoff, M. Slavik, and F. M. Muggia, “Cis diamminedichloroplatinum (II). A new anticancer drug,” Annals of Internal Medicine, vol. 86, no. 6, pp. 803–812, 1977. View at Publisher · View at Google Scholar · View at Scopus
  23. P. J. Loehrer and L. H. Einhorn, “Drugs five years later. Cisplatin,” Annals of Internal Medicine, vol. 100, no. 5, pp. 704–713, 1984. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Pucci, M. Kasten, and A. Giordano, “Cell cycle and apoptosis,” Neoplasia, vol. 2, no. 4, pp. 291–299, 2000. View at Publisher · View at Google Scholar · View at Scopus
  25. W. S. El-Deiry, T. Tokino, V. E. Velculescu et al., “WAF1, a potential mediator of p53 tumor suppression,” Cell, vol. 75, no. 4, pp. 817–825, 1993. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Cheng, P. Olivier, J. A. Diehl et al., “The p21(Cip1) and p27(Kip1) CDK ‘inhibitors’ are essential activators of cyclin D-dependent kinases in murine fibroblasts,” EMBO Journal, vol. 18, no. 6, pp. 1571–1583, 1999. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Dasari and P. B. Tchounwou, “Cisplatin in cancer therapy: molecular mechanisms of action,” European Journal of Pharmacology, vol. 740, pp. 364–378, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. B.-Y. Zhang, Y.-M. Wang, H. Gong et al., “Isorhamnetin flavonoid synergistically enhances the anticancer activity and apoptosis induction by cis-platin and carboplatin in non-small cell lung carcinoma (NSCLC),” International Journal of Clinical and Experimental Pathology, vol. 8, no. 1, pp. 25–37, 2015. View at Google Scholar · View at Scopus
  29. T. K. MacLachlan, N. Sang, and A. Giordano, “Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer,” Critical Reviews in Eukaryotic Gene Expression, vol. 5, no. 2, pp. 127–156, 1995. View at Publisher · View at Google Scholar · View at Scopus
  30. J. W. Harper and S. J. Elledge, “Cdk inhibitors in development and cancer,” Current Opinion in Genetics and Development, vol. 6, no. 1, pp. 56–64, 1996. View at Publisher · View at Google Scholar · View at Scopus
  31. P. S. Morahan, J. A. Munson, L. G. Baird, A. M. Kaplan, and W. Regelson, “Antitumor action of pyran copolymer and tilorone against Lewis lung carcinoma and B-16 melanoma,” Cancer Research, vol. 34, no. 3, pp. 506–511, 1974. View at Google Scholar · View at Scopus
  32. M.-F. Chen, C.-M. Yang, C.-M. Su, and M.-L. Hu, “Vitamin C protects against cisplatin-induced nephrotoxicity and damage without reducing its effectiveness in C57BL/6 mice xenografted with lewis lung carcinoma,” Nutrition and Cancer, vol. 66, no. 7, pp. 1085–1091, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. N. Pabla, S. Huang, Q.-S. Mi, R. Daniel, and Z. Dong, “ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis,” Journal of Biological Chemistry, vol. 283, no. 10, pp. 6572–6583, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. J. A. Diehl, “Cycling to cancer with cyclin D1,” Cancer Biology and Therapy, vol. 1, no. 3, pp. 226–231, 2002. View at Publisher · View at Google Scholar · View at Scopus
  35. J. Brugarolas, C. Chandrasekaran, J. I. Gordon, D. Beach, T. Jacks, and G. J. Hannon, “Radiation-induced cell cycle arrest compromised by p21 deficiency,” Nature, vol. 377, no. 6549, pp. 552–557, 1995. View at Publisher · View at Google Scholar · View at Scopus
  36. I. Arany and R. L. Safirstein, “Cisplatin nephrotoxicity,” Seminars in Nephrology, vol. 23, no. 5, pp. 460–464, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. Y. Ito, Y. Arahata, Y. Goto et al., “Cisplatin neurotoxicity presenting as reversible posterior leukoencephalopathy syndrome,” American Journal of Neuroradiology, vol. 19, no. 3, pp. 415–417, 1998. View at Google Scholar · View at Scopus
  38. A. Ekborn, A. Lindberg, G. Laurell, I. Wallin, S. Eksborg, and H. Ehrsson, “Ototoxicity, nephrotoxicity and pharmacokinetics of cisplatin and its monohydrated complex in the guinea pig,” Cancer Chemotherapy and Pharmacology, vol. 51, no. 1, pp. 36–42, 2003. View at Publisher · View at Google Scholar · View at Scopus