Research Article
Antitumor Effect of Zhihuang Fuzheng Soft Capsules on Tumor-Bearing Mice
Table 7
Effect of ZFSC on CD4/CD8 value, NK cell activity, and PD1 and PDL1 content in A-549 tumor-bearing mice.
| Groups | Dose (mg/kg) | Number of animals | CD4/CD8 | NK (nmol/L) | PD1 (pg/mL) | PDL1 (ng/L) |
| Model | — | 8 | 0.089 ± 0.006 | 79.7 ± 9.4 | 57.0 ± 5.4 | 37.6 ± 2.5 |
| Positive drug | 5500 | 8 | 0.094 ± 0.009 | 86.7 ± 13.7 | 59.9 ± 4.6 | 37.1 ± 2.6 |
| ZFSC | 275 | 8 | 0.089 ± 0.005 | 82.1 ± 8.8 | 60.6 ± 8.7 | 37.3 ± 3.0 | 550 | 8 | 0.087 ± 0.010 | 86.2 ± 11.6 | 65.8 ± 10.4 | 36.6 ± 4.2 | 1100 | 8 | 0.087 ± 0.010 | 84.6 ± 6.7 | 65.0 ± 5.9 | 38.4 ± 3.3 |
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