Research Article

Antitumor Effect of Zhihuang Fuzheng Soft Capsules on Tumor-Bearing Mice

Table 7

Effect of ZFSC on CD4/CD8 value, NK cell activity, and PD1 and PDL1 content in A-549 tumor-bearing mice.

GroupsDose (mg/kg)Number of animalsCD4/CD8NK (nmol/L)PD1 (pg/mL)PDL1 (ng/L)

Model80.089 ± 0.00679.7 ± 9.457.0 ± 5.437.6 ± 2.5

Positive drug550080.094 ± 0.00986.7 ± 13.759.9 ± 4.637.1 ± 2.6

ZFSC27580.089 ± 0.00582.1 ± 8.860.6 ± 8.737.3 ± 3.0
55080.087 ± 0.01086.2 ± 11.665.8 ± 10.436.6 ± 4.2
110080.087 ± 0.01084.6 ± 6.765.0 ± 5.938.4 ± 3.3