Research Article

Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model

Figure 1

The loading efficacy (LE%) of HBsAg in alum suspension vaccine formulations (Al, AlCh, AlS, and AlChS). Each bar represents mean LE%  ± standard deviation. Natural adjuvant formulations showed significantly higher LE% compared to alum-adjuvanted HBsAg. and compared against alum adjuvant formulation.