Research Article

Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model

Figure 3

HBsAg-specific IgG titers of mice immunized with different formulations of hepatitis B adjuvanted vaccine. Group of 6 mice was immunized with various HBsAg formulations. Pool of sera for each group collected after 28 days and serum anti-HBs antibody was determined. Each bar corresponds to the group means ± SD from 3 independent experiments.