Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model
Levels of serum anti-HBsAg IgG subclass elicited in mice immunized with different formulations of the hepatitis B vaccine. Values are expressed as mean of antibody level from 3 independent experiments ± standard variation. (AlChS versus unadjuvanted group) in levels of IgG1; (S versus AlCh group), (AlChS versus AlCh group), and (AlChS versus AlS group) levels of IgG2b.
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