Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model

Table 1

Composition of adjuvant systems formulations used in the study.

	1; (Negative control)	2; (Unadjuvanted)	3; (Al)	4; (Ch)	5; (S)	6; (AlCh)	7; (AlS)	8; (AlChS)
PBS	x
HBsAg (1 μg/mL)		x
HBsAg (0.1 μg/mL)			x	x	x	x	x	x
Alum (0.5 mg/mL)			x			x	x	x
Chitosan (0.5 mg/mL)				x		x		x
Sodium alginate (5 mg/mL)					x		x	x