Isolation of 4,5-O-Dicaffeoylquinic Acid as a Pigmentation Inhibitor Occurring in Artemisia capillaris Thunberg and Its Validation In Vivo

Figure 3

Inhibitory effect of the active fraction ACMF09 and 4,5-diCQA on tyrosinase activity. The inhibition of cell-free tyrosinase activity was determined using mushroom tyrosinase. Azelaic acid (AZ) was used as a positive control. The results are expressed as percentages of the control, and the data are mean ± SEM of three independent experiments. as compared to the untreated control.