Isolation of 4,5-O-Dicaffeoylquinic Acid as a Pigmentation Inhibitor Occurring in Artemisia capillaris Thunberg and Its Validation In Vivo

Figure 7

Effect of the A. capillaris extract, active fraction ACMF09, and 4,5-diCQA on melanocyte cell viability. B16-F10 melanocytes were treated with test samples at the indicated concentrations for 48 h. Cell viability was determined using the MTT assay. Azelaic acid (AZ) was used as a positive control. The results are expressed as percentages of the control, and the data are mean ± SEM of three independent experiments.