Electroacupuncture Alleviates Depressive-Like Symptoms and Modulates BDNF Signaling in 6-Hydroxydopamine Rats

Figure 4

EA at 100 Hz modulated the abnormal expression of BDNF and TrkB in the midbrain and in the hippocampus. BDNF levels were measured by ELISA on the lesioned side and unlesioned side in the ventral midbrain (a) and the hippocampus (c), respectively. TrkB expressions were measured by western blotting on the unlesioned side and lesioned side in the ventral midbrain (b) and the hippocampus (d), respectively. β-actin was used as an internal control. Data represent mean ± SEM (-6 per group). , , and versus the sham group; and versus the model.