Electroacupuncture Restores 5-HT System Deficit in Chronic Mild Stress-Induced Depressed Rats

Figure 1

Body weight (a), sucrose preference (b), crossing pieces (c), rearing times (d), and immobile time (e) in CUMS rats with each treatment. CON: normal control group without stress stimuli and any treatments; CUMS: CUMS group exposed to stress stimuli for 8 weeks without any treatments; Flu: CUMS + fluoxetine group exposed to stress stimuli for 8 weeks and fluoxetine treatment at the dosage of 20 mg/kg from the 5th to the 8th week; EA: CUMS + EA group exposed to stress stimuli for 8 weeks and EA treatment (points at Baihui and Yintang) from the 5th to the 8th week; sham EA: CUMS + nonacupoint group exposed to stress stimuli for 8 weeks and without EA treatment (points at EX-HN3 and GV20 without electrostimulator) from the 5th to the 8th week; A, CUMS compared with CON; B, Flu compared with CUMS; C, EA compared with CUMS; D, EA compared with sham EA; E, sham EA compared with CUMS.

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