Research Article

Effect of Heweianshen Decoction on Orexin-A and Cholecystokinin-8 Expression in Rat Models of Insomnia

Table 2

Effect of the Heweianshen decoction on orexin-A levels in hypothalamus of rat model of insomnia ().

GroupOrexin-A (pg/mg)

Blank group1019.26 ± 3.38
PCPA model group1029.67 ± 5.12
Low-dose group1026.71 ± 4.10
Medium-dose group1022.03 ± 2.81
High-dose group1020.97 ± 3.26

Notes: blank group and model group were given normal saline 1 mL/100 g; the low-, medium-, and high-dose HAD-treated groups were given Heweianshen decoction of 5.25, 10.5, and 21 g⋅kg−1⋅d−1, respectively. Compared with the blank group, . Compared with the model group, .