Paeoniflorin and Albiflorin Attenuate Neuropathic Pain via MAPK Pathway in Chronic Constriction Injury Rats

Figure 5

Effects of PF and AF on CCI-Augmented p-p38 MAPK protein in the spinal cord dorsal horn at the 15th day after CCI surgery. Immunofluorescent labeling p-p38 in Sham + vehicle (a), CCI + vehicle (b), CCI + PF (c), and CCI + AF (d). Scale bar = 100 μm. ((e)–(g)) Double-immunofluorescent labeling p-p38/Iba-1. Scale bar = 50 μm. (h) Quantification of p-p38 levels in the dorsal horn. The Western blot results are presented as a fold of Sham control, data were expressed as mean ± SE, and rats/group. compared with Sham + vehicle group and compared with CCI + vehicle group.

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