Antimutagenic Compounds of White Shrimp (Litopenaeus vannamei): Isolation and Structural Elucidation

Table 1

Antimutagenicity of white shrimp muscle-crude chloroform extract and its methanolic and hexanic fractions tested on Salmonella typhimurium tester strains.

Dose (mg/plate)	Crude extract	Methanolic fraction	Hexanic fraction
TA98
5	94.6 ± 1.1	95.6 ± 0.6	67.8 ± 1.1
0.5	12.6 ± 12.6	31.3 ± 13.8	54.7 ± 14.3
0.05	10.2 ± 12.4	10.2 ± 4.2	−10.2 ± 9.8
TA100
5	95.3 ± 2.4	95.9 ± 1.9	32.7 ± 8.0
0.5	2.5 ± 14.6	11.5 ± 6.0	0.2 ± 11.1
0.05	−14.5 ± 17.2	−8.6 ± 12.8	−34.9 ± 9.1

Results are presented as the percentage of inhibition of AFB₁ mutation and are representative of three repetitions.
Values with different letters within a row are significantly different (). Spontaneous revertants were 31 ± 3 and 117 ± 6, and AFB₁ control (500 ng) induced 625 ± 26 and 958 ± 27 revertants/plate for TA98 and TA100, respectively.