Research Article

Antimutagenic Compounds of White Shrimp (Litopenaeus vannamei): Isolation and Structural Elucidation

Table 2

Antimutagenicity of fractions obtained after RP-HPLC fractionation of a methanolic fraction from white shrimp muscle tested on Salmonella typhimurium tester strains.

TA98TA100

M122.8 ± 5.7 27.1 ± 10.2
M2 66.5 ± 5.1 66.1 ± 5.6
M3 63.1 ± 10.1 17.7 ± 8.5
M4 58.6 ± 10.7 72.5 ± 7.3
M5 70.1 ± 3.6 31.0 ± 10.7
M666.5 ± 1.2 42.8 ± 2.1
M7 41.1 ± 11.7 30.9 ± 7.4
M880.0 ± 7.0 63.7 ± 4.6
M9 40.8 ± 11.7 53.0 ± 9.3
M10 45.0 ± 11.4 46.59 ± 6.9
M11 48.6 ± 9.6 56.2 ± 11.6
M12 68.0 ± 5.5 79.6 ± 4.3
M13 52.6 ± 11.4 53.3 ± 2.9
M14 74.8 ± 7.4 59.2 ± 7.2
M15 71.9 ± 4.8 71.0 ± 7.1

Results are presented as the percentage of inhibition of AFB1 mutation and are representative of three repetitions.
Values with different letters within a column are significantly different (). Spontaneous revertants/plate were 31 ± 3 and 117 ± 6 and AFB1 control (500 ng) were 625 ± 26 and 958 ± 27 revertants/plate for TA98 and TA100, respectively.