Formulation of Propolis Phenolic Acids Containing Microemulsions and Their Biopharmaceutical Characterization

Table 4

Mean droplet size and PDI of o/w microemulsions.

Ratio of S : CoS	Mean droplet size ± SD (nm)/PDI
	24 hours		1 week
	ME with EtOH	ME with ethanolic propolis extract	ME with EtOH	ME with ethanolic propolis extract
2 : 1	34.95 ± 0.19	43.69 ± 0.41	34.97 ± 0.17	43.49 ± 0.46
	0.299 ± 0.003	0.274 ± 0.020	0.300 ± 0.005	0.268 ± 0.017
3 : 1	40.67 ± 0.32	48.83 ± 0.31	40.45 ± 0.35	48.62 ± 0.42
	0.310 ± 0.004	0.274 ± 0.006	0.304 ± 0.003	0.285 ± 0.020
4 : 1	46.80 ± 0.86	55.30 ± 0.45	46.23 ± 0.29	55.42 ± 0.36
	0.312 ± 0.005	0.285 ± 0.022	0.312 ± 0.005	0.275 ± 0.008
5 : 1	51.53 ± 0.56	62.10 ± 0.39	51.34 ± 0.35	62.17 ± 0.54
	0.312 ± 0.002	0.271 ± 0.009	0.305 ± 0.008	0.272 ± 0.007
6 : 1	57.10 ± 0.43	66.24 ± 0.41	57.32 ± 0.17	66.45 ± 0.50
	0.309 ± 0.004	0.271 ± 0.007	0.307 ± 0.009	0.271 ± 0.005
7 : 1	61.85 ± 0.41	72.02 ± 0.62	62.07 ± 0.10	72.15 ± 0.53
	0.299 ± 0.004	0.266 ± 0.006	0.299 ± 0.009	0.269 ± 0.009
8 : 1	65.88 ± 0.63	79.58 ± 1.07	66.78 ± 0.62	77.50 ± 0.15
	0.300 ± 0.003	0.288 ± 0.021	0.295 ± 0.002	0.268 ± 0.003
9 : 1	69.56 ± 0.68	80.24 ± 1.12	70.26 ± 0.85	80.68 ± 0.13
	0.292 ± 0.003	0.274 ± 0.011	0.289 ± 0.005	0.267 ± 0.002