Research Article

Untargeted Metabolomics Reveals Intervention Effects of Total Turmeric Extract in a Rat Model of Nonalcoholic Fatty Liver Disease

Table 2

List and change trends of differential metabolites.

NumberRT
(min)
Mass
(m/z)
MetabolitesFormulaModel
trend
HD-TE
trend

10.95206.04192-C-Methyl-D-erythritol 4-phosphateC5H13O7P#
25.12229.03715-PhosphoribosylamineC5H12NO7P##
314.46360.1873CortisoneC20H28O5##
415.24284.1776Androsta-1,4-diene-3,17-dioneC19H24O2##
515.95476.2441all-trans-Retinoyl-beta-glucuronideC26H36O8##
616.17535.36681-Acyl-sn-glycero-3-phosphoethanolamine
(LysoPE)
C27H54NO7P
716.34434.24631-Acyl-sn-glycerol-3-phosphate
LPA(18:2(9Z,12Z)/0:0)
C20H39O7P##
817.19757.5842Phosphatidylethanolamine
PE(15:0/22:2(13Z,16Z))
C42H80NO8P#
917.20164.12202,4,6-UndecatrienalC11H16O##
1017.42368.2563CortolC20H36O5##
1117.45332.235121-HydroxypregnenoloneC20H32O3##
1217.46366.2473CortoloneC20H34O5##
1318.49408.30384Z,7Z,10Z,13Z,16Z,19Z,22Z,25Z-Octacosaoctaenoic acid (fatty acid)C28H40O2##
1419.31588.2944D-UrobilinC33H40N4O6##
1520.48424.30081-Alkyl-sn-glycero-3-phosphate
(1-octadecyl lysophosphatidic acid)
C20H45O6P##
1622.63428.3684Cholesteryl ester (CE(12:0))C29H48O2##
1722.74686.49131,2-Diacyl-sn-glycerolC45H66O5#
1822.76720.4941Phosphatidylglycerol [PG(14:0/18:1(9Z))]C38H73O10P##
1922.93727.4572Phosphatidyl-L-serine
PS(14:1(9Z)/18:3(9Z,12Z,15Z))
C38H66NO10P##
2023.04660.50341,2-Diacyl-sn-glycerol 3-phosphate
PA(P-20:0/14:0)
C37H73O7P##

Compared to the normal group. Compared to the model group. The significantly changed biomarkers were flagged with () downregulated, () upregulated, and (—) invalid data; P < 0.05, P < 0.01.