Research Article

Tongxinluo Enhances Neurogenesis and Angiogenesis in Peri-Infarct Area and Subventricular Zone and Promotes Functional Recovery after Focal Cerebral Ischemic Infarction in Hypertensive Rats

Table 1

Tongxinluo treatment ameliorated neurological function without affecting infarct volume.

Day 3Day 7Day 14

Vehicle
 Bederson score2.75 (2.5, 3)2.5 (2.25, 2.75)1.5 (1.25, 1.75)
 Infarct volume24.85 ± 2.78%19.36 ± 2.96%16.64 ± 1.62%
Tongxinluo
 Bederson score2.75 (2.25, 3) 1.5 (1.25, 2)1.0 (1, 1.75)
 Infarct volume25.56 ± 2.44%20.62 ± 2.25%17.58 ± 1.58%

MCAO: middle cerebral artery occlusion.
Values are mean ± SEM or median and quartile range from six rats. compared with the vehicle group.