Piperine Plays an Anti-Inflammatory Role in Staphylococcus aureus Endometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice

Figure 3

Expression of inflammatory cytokines. (a) The protein production levels of TNF-α, IL-1β, IL-6, and IL-10 in uterus tissues. (b) The mRNA levels of TNF-α, IL-1β, IL-6, and IL-10 in uterus tissues are shown. CG: control group. S. aureus: S. aureus group. The 25, 50, and 100 indicate the piperine treatment groups, which were given piperine at 25 mg/kg, 50 mg/kg, and 100 mg/kg per animal. DEX: DEX group, treated with 5 mg/kg. The data are represented as the mean ± SD. represents statistical significance compared with the CG and represents statistical significance compared with the S. aureus group.

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