Research Article
Effect of Huai Qi Huang on Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through miR-200a
Figure 4
Huai Qi Huang (HQH) inhibited epithelial-mesenchymal transition (EMT) in UUO rats. (a) Immunohistochemical staining shows E-cadherin+ epithelial cells and α-SMA+ myofibroblasts distributed in sham operation and obstructed kidney in each group (200x). (b) Representative bands for E-cadherin and α-SMA protein detected by Western blots in obstructed kidneys of UUO rats. (c) Relative protein levels of E-cadherin or α-SMA to GAPDH in each group. versus vehicle-treated UUO rats on the same day after obstruction. Five rats in each dosage group. The bars show mean ± SEM.
(a) |
(b) |
(c) |