Research Article

An Extract of Chinpi, the Dried Peel of the Citrus Fruit Unshiu, Enhances Axonal Remyelination via Promoting the Proliferation of Oligodendrocyte Progenitor Cells

Figure 7

A hypothesis of the fate of oligodendrocyte linages in remyelination. Demyelination triggers the proliferation and recruitment of OPC. Ddx54+ OPC differentiate into MBP21.5-expressing oligodendrocytes (OL) that obtain myelinating capacity, while Ddx54āˆ’ OPC differentiate into MBP21.5āˆ’ OL that cannot myelinate axons.