Review Article

An Overview of Systematic Reviews of Danhong Injection for Ischemic Stroke

Table 1

Characteristics of systematic reviews.

Author, yearElectronic databases (year)Number of studies included (number of study population)Intervention (participants)Comparison interventions (participants)Course (d)Main outcomeTypes of participantsQuality assessmentQuality of primary studies

Hu et al., 2009 [13]CNKI, Wanfang, VIP
(1994–2008)
12
(950)
DHI + RT
(477)
CDI, XSTI, VI, BC + RT
(473)
14–21 d①②AISJadadPoor

Xu et al., 2010 [14]CNKI, Wanfang, VIP, CBM
(NA)
9
(996)
DHIXDI, CXQI HI, RT, DI, CDI, XSTI14–30 d①②AISJadadPoor

Xiong et al., 2014 [15]CBM, FMJS, CNKI, Wanfang, VIP, duxiu
(2009–2014)
21
(2725)
DHINANAISJadadPoor

Ye et al., 2010 [16]CNKI, PubMed
(2004–2009)
45
(4027)
DHICDI, RT, VI, XSTI, CXQI, and so forth7–30 dISJadadPoor

Yang and Zeng, 2012 [17]CNKI, Wanfang
(2006–2010)
27
(2583)
DHI + RTDSI, CDI + RTNA①②ISCochrane HandbookB
Grade

Liu et al., 2014 [18]CNKI, Wanfang
(2004–2014)
9
(885)
DHI + RTRT7–14 dAISCochrane HandbookB or C
Grade

Peng et al., 2010 [19]Medline, Embase, CBM, CNKI, VIP, Wanfang
(2000–2010)
29
(3191)
DHICDI14–30 d①②③AISCochrane HandbookB
Grade

Ma et al., 2012 [20]CBM, VIP, Medline, Cochrane
(up to 2011)
14
(1112)
DHI + RTRT14–21 d①②AISJadadPoor

DHI, Danhong injection; RT, routine therapy; CDI, Compound Danshen Injection; XSTI, Xuesetong injection; VI, Venoruton injection; BC, black control; XDI, Xiangdan injection; CXQI, Chuanxiongqin injection; HI, hydroxyethyrutin injection; DI, Dextran injection; NA, not available; DSI, Danshen injection; AIS, acute ischemic stroke; IS, ischemic stroke; FMJS, foreign medical journal full-text service.
① Clinical efficiency; ② neurological deficits score; ③ deterioration and mortality.