Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression
Table 1
The top five most common herbal-pairs used for bladder cancer treatment.
Rank
Herbal-pair
Support factor (%)
Confidence factor (%)
Number of prescriptions (%)
1
Hedyotisdiffusa; Scutellaria barbata
18.0
73.22
361 (18.0)
N/A
N/A
178 (50.4)#
N/A
N/A
157 (75.12)
2
Poria cocos; Polyporus umbellatus
13.8
54.12
277 (13.8)
N/A
N/A
280 (79.35)#
N/A
N/A
146 (69.86)
3
Desmodium styracifolium; Lonicera japonica Thunb.
11.7
60.30
235 (11.7)
N/A
N/A
253 (71.59)#
N/A
N/A
113 (54.07)
4
Herba Lophatheri; liquorice root
10.0
58.92
202 (10.0)
N/A
N/A
196 (55.42)#
N/A
N/A
104 (49.76)
5
Atractylodes; Rhizoma Alismatis
8.8
43.32
178 (8.8)
N/A
N/A
121 (34.04)#
N/A
N/A
5 (2.39)
Note: the total number of prescriptions: 2004; #354 [10]; 209 [11]. N/A: not available. The association rules were analyzed by software SPSS Modeler 14.1 (Apriori).