Research Article

Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression

Table 1

The top five most common herbal-pairs used for bladder cancer treatment.

RankHerbal-pairSupport factor (%)Confidence factor (%)Number of prescriptions (%)

1Hedyotisdiffusa;
Scutellaria barbata
18.073.22361 (18.0)
N/AN/A178 (50.4)#
N/AN/A157 (75.12)

2Poria cocos;
Polyporus umbellatus
13.854.12277 (13.8)
N/AN/A280 (79.35)#
N/AN/A146 (69.86)

3Desmodium styracifolium;
Lonicera japonica Thunb.
11.760.30235 (11.7)
N/AN/A253 (71.59)#
N/AN/A113 (54.07)

4Herba Lophatheri;
liquorice root
10.058.92202 (10.0)
N/AN/A196 (55.42)#
N/AN/A104 (49.76)

5Atractylodes;
Rhizoma Alismatis
8.843.32178 (8.8)
N/AN/A121 (34.04)#
N/AN/A5 (2.39)

Note: the total number of prescriptions: 2004; #354 [10]; 209 [11]. N/A: not available. The association rules were analyzed by software SPSS Modeler 14.1 (Apriori).