The Effects of Xiangqing Anodyne Spray on Treating Acute Soft-Tissue Injury Mainly Depend on Suppressing Activations of AKT and p38 Pathways

Figure 3

Effects of XQAS on inflammation-related signaling pathway with IκBα expression in cytosol (a), NF-κB p65 mRNA expression (b), NF-κB p65 expression in cytosol extraction (CE) and nuclei extraction (NE) (c), and expressions of total AKT (t-AKT), Ser⁴⁷³ phosphorylation of AKT (p-AKT), total p38 (t-p38), Thr¹⁸⁰/Tyr¹⁸² phosphorylation of p38 (p-p38), total JNK (t-JNK), and Thr¹⁸³/Tyr¹⁸⁵ phosphorylation of JNK (p-JNK) in the control (Ctrl), acute STI model (Mod), high-dose XQAS-treated (HXQAS), low-dose XQAS-treated (LXQAS), CPS-treated (CPS), and IHS-treated (IHS) group after modeling with or without repeated drug treatment for 8 h. The data were shown as mean ± SD ( per group). ; .

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