Sakuranetin Inhibits Inflammatory Enzyme, Cytokine, and Costimulatory Molecule Expression in Macrophages through Modulation of JNK, p38, and STAT1

Figure 6

Sakuranetin attenuates LPS-induced STAT1 phosphorylation. Cells were pretreated with sakuranetin for 1 h and then stimulated with LPS for 3 h. Total protein was extracted and assayed for phosphorylated STAT1 by Western blotting. Tubulin was used as an internal control. (a) One of the three experiments is shown. (b) The band density of phosphorylated STAT1 was normalized with tubulin. and versus controls (cells treated with LPS only).

(a)

(b)