The Efficacy and Safety of the Combination of Total Glucosides of Peony and Leflunomide for the Treatment of Rheumatoid Arthritis: A Systemic Review and Meta-Analysis

Table 1

The characteristics of the included studies.

Author	Participants		Interventions		Duration	Outcomes
	Experiment	Control	Experiment	Control
Wu et al. [18]	50	50	TGP + LEF	LEF	12 weeks	ESR, CRP, RF, AE
Li [19]	48	48	TGP + LEF	LEF	NA	Therapeutic effects, ESR, RF, AE
Dong [20]	33	33	TGP + LEF	LEF	12 weeks	ESR
Tao et al. [21]	52	52	TGP + LEF	LEF	4 weeks	Therapeutic effects, AE
Yu and Zhang [22]	39	40	TGP + LEF	LEF	24 weeks	ESR, CRP, AE
Si [23]	17	21	TGP + LEF	LEF	24 weeks	Therapeutic effects, ESR, RF
Ma [24]	40	40	TGP + LEF	LEF	12 weeks	AE
Zhao and Liu [25]	40	40	TGP + LEF	LEF	12 weeks	Therapeutic effects, ESR, CRP, RF, AE

Note: TGP: total glucosides of peony; LEF: leflunomide; ESR: erythrocyte sedimentation rate; CRP: C reaction protein; RF: rheumatoid factor; AE: adverse event; NA: not available.