Phytochemical and Antinociceptive, Anti-Inflammatory, and Antioxidant Studies of Smilax larvata (Smilacaceae)

Figure 6

Antinociceptive mechanism of SLG. (a) and (b) represent the mean ± SEM of the number of paw flinches during the first (a) or the second phase (b) of the formalin test in rats pretreated with saline (Veh) or naloxone (Nal) plus SLG. when compared to vehicle (V) + SLG 200-treated group. when compared to vehicle- (V-) treated group. (c) represents the effect of SLG treatment on intestinal motility in rats. Data are expressed as the mean ± SEM of percentage of intestinal motility inhibition in animals treated with vehicle (V), SLG, or morphine (M). when compared to vehicle- (V-) treated group. (d) Effect of SLG treatment (200 mg/Kg) on mustard oil-induced paw flinches in rats. Data are expressed as the mean ± SEM of the number of paw flinches observed during 30 min after mustard or corn oil treatment. when compared to vehicle (V) + corn oil-treated group.

(a)

(b)

(c)

(d)