Review Article

Effectiveness and Safety of the Combination of the Traditional Chinese Medicine Prescription Jade Screen and Desloratadine in the Treatment of Chronic Urticaria: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 1

The basic characteristics of the 16 RCT studies.

Author/yearGroupsSample sizeAge (median or mean or range)Course of diseaseCourse of treatment (days) Intervention Outcomes

Zhang et al., 2008 [16]EP5019–6021.3 months28①②③
CG5019–6022.5 months28
Jiang et al., 2009 [17] EP3218–526–24 weeks84①②④
CG3018–506–25 weeks84
Hu et al., 2011 [18] EP2821–589 weeks–11 months28
CG2621–589 weeks–11 months28
Cai, 2012 [19] EP6218–752 months–10 years40①②③④
CG5818–752 months–10 years40
Liang, 2012 [20] EP601.1 ± 0.25 years28①②③
CG601.6 ± 0.5 years28
Qu, 2013 [21] EP4312–456 weeks–2 years28①②
CG4313–436 weeks–2 years28
Su et al., 2013 [22] EP5912–60≥6 weeks28①②③
CG5812–60≥6 weeks28
Wang, 2013 [23] EP9935–603 months–12 years28①②③
CG8235–603 months–12 years28
Wei and Zhang, 2013 [24] EP41≥6 weeks28①②③
CG40≥6 weeks28
Zhu, 2013 [25] EP362 months–3 years21①②③
CG282 months–3 years21
Xie, 2014 [26] EP6016–582 months–8 years56①②
CG6016–582 months–8 years56
Fu et al., 2015 [27] EP100 years56①②③④⑤
CG110 years56
Li, 2015 [28] EP6218–562 months–3 years28①②
CG4820–582 months–4 years28
Tian and Huang, 2015 [29] EP8618–628 weeks–5 years28①②③⑤
CG8618–639 weeks–7 years28
Qin et al., 2016 [30] EP48 years28①②③
CG48 years28
Zhao, 2016 [31] EP35 years30①②③④
CG35 years30

(1) Desloratadine: 5 mg po qd; (2) Jade Screen: po tid + Desloratadine: 5 mg po qd; (3) desloratadine: 8.8 mg po qd; (4) Jade Screen: po tid + desloratadine: 8.8 mg po qd; EP: experiment group; CG: control group; ① total effective rate; ② adverse reaction; ③ recurrence rate; ④ symptom score; ⑤ serum IgE level.