Research Article

Isolation and Characterization of Isofraxidin 7-O-(6′-O-p-Coumaroyl)-β-glucopyranoside from Artemisia capillaris Thunberg: A Novel, Nontoxic Hyperpigmentation Agent That Is Effective In Vivo

Figure 5

Dose-dependent effect of PTU on pigmentation in zebrafish embryos. Zebrafish were treated with PTU at concentrations of 25, 50, 75, 100, and 200 μM. PTU treatment suppressed the production of black pigment spots (melanization) in the larva. Scale bar = 250 μm.