Isolation and Characterization of Isofraxidin 7-O-(6′-O-p-Coumaroyl)-β-glucopyranoside from Artemisia capillaris Thunberg: A Novel, Nontoxic Hyperpigmentation Agent That Is Effective In Vivo

Figure 8

Effect of compound 1 on melanocyte numbers and surface area in zebrafish embryos. (a) Box and whisker plot of melanocyte numbers in the head region in embryos treated with PTU, isofraxidin, or compound 1 at 48 hpf. (b) Surface area of melanocytes in the treated and untreated embryos at 48 hpf. compared to the untreated larva.

(a)

(b)