The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction

Table 1

and pEC₅₀ values of concentration-response curves to histamine in the absence and presence of Schinus terebinthifolius (St) bark extract, hydroxyzine (HXZ), and their associations.

Treatment	(%)	pEC50
Control
St 250 μg/mL
St 500 μg/mL
St 1,000 μg/mL
HXZ 0.125 μM
HXZ 0.250 μM
St 250 μg/mL + HXZ 0.125 μM
St 500 μg/mL + HXZ 0.250 μM

Values represent the mean ± SEM (). different compared to the control. groups are statistically different from each other. (One-way ANOVA followed by Tukey’s multiple comparisons test, .)